Authors: L Funk

References: Osteoarthritis and Cartilage, Volume 13, Supplement A, page S80, 2005


The aim of this study was to compare a synthetic Hyaluronan (OstenilPTMP) to a corticosteroid injection (Depomedrone) for primary subacromial impingement of the shoulder.

In a retrospective review, thirty one patients with primary subacromial impingement of the shoulder were randomly given either a 40mg Depomedrone injection or Ostenil injection. No patients had undergone previous surgery. All had physiotherapy following the injection. Patients were given a Pain Diary with a ten point visual analogue scale to complete.

There was no difference between the two groups with regard to age and sex. Both steroid and Ostenil reduce the pain score in the first two to four hours post-injection, but in the Depomedrone group the pain score increases significantly from 12 hours to 2 days post-injection. This effect is not observed with Ostenil. This difference is significant (p<0.05) between 18 hours and 3 days post-injection. From 4 days the pain score is similar, with an equal reduction in pain in the two groups. Conclusions: Ostenil Hyaluronan appears to be as effective as Depomedrone in reducing subacromial impingement pain, but does not produce the pain surge associated with Depomedrone in the first few days post-injection.

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